An integrated whole genome analysis of Mycobacterium tuberculosis reveals insights into relationship between its genome, transcriptome and methylome

Abstract Human tuberculosis disease (TB), caused by Mycobacterium tuberculosis (Mtb), is a complex disease, with a spectrum of outcomes. Genomic, transcriptomic and methylation studies have revealed differences between Mtb lineages, likely to impact on transmission, virulence and drug resistance. Ho...

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Bibliographic Details
Main Authors: Paula J. Gomez-Gonzalez, Nuria Andreu, Jody E. Phelan, Paola Florez de Sessions, Judith R. Glynn, Amelia C. Crampin, Susana Campino, Philip D. Butcher, Martin L. Hibberd, Taane G. Clark
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-41692-2