Terminal Differentiation of Adult Hippocampal Progenitor Cells Is a Step Functionally Dissociable from Proliferation and Is Controlled by Tis21, Id3 and NeuroD2

Terminal Differentiation of Adult Hippocampal Progenitor Cells Is a Step Functionally Dissociable from Proliferation and Is Controlled by Tis21, Id3 and NeuroD2

Cell proliferation and differentiation are interdependent processes. Here, we have asked to what extent the two processes of neural progenitor cell amplification and differentiation are functionally separated. Thus, we analyzed whether it is possible to rescue a defect of terminal differentiation in...

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Bibliographic Details
Main Authors: Laura Micheli, Manuela Ceccarelli, Roberta Gioia, Giorgio D’Andrea, Stefano Farioli-Vecchioli, Marco Costanzi, Daniele Saraulli, Vincenzo Cestari, Felice Tirone
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
hippocampal neurogenesis
neural differentiation
neural progenitor cells
NEUROD2
Id3
Tis21
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00186/full

Internet

http://journal.frontiersin.org/article/10.3389/fncel.2017.00186/full

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