Validation study of genetic biomarkers of response to TNF inhibitors in rheumatoid arthritis.

Validation study of genetic biomarkers of response to TNF inhibitors in rheumatoid arthritis.

Genetic biomarkers are sought to personalize treatment of patients with rheumatoid arthritis (RA), given their variable response to TNF inhibitors (TNFi). However, no genetic biomaker is yet sufficiently validated. Here, we report a validation study of 18 previously reported genetic biomarkers, incl...

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Bibliographic Details
Main Authors: Rosario Lopez-Rodriguez, Eva Perez-Pampin, Ana Marquez, Francisco J Blanco, Beatriz Joven, Patricia Carreira, Miguel Angel Ferrer, Rafael Caliz, Lara Valor, Javier Narvaez, Juan D Cañete, Maria Del Carmen Ordoñez, Sara Manrique-Arija, Yiannis Vasilopoulos, Alejandro Balsa, Dora Pascual-Salcedo, Manuel J Moreno-Ramos, Juan Jose Alegre-Sancho, Federico Navarro-Sarabia, Virginia Moreira, Rosa Garcia-Portales, Enrique Raya, Cesar Magro-Checa, Javier Martin, Juan J Gomez-Reino, Antonio Gonzalez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5937760?pdf=render

Internet

http://europepmc.org/articles/PMC5937760?pdf=render

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