TSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation.

Although much effort has been directed at dissecting the mechanisms of central tolerance, the role of thymic stromal cells remains elusive. In order to further characterize this event, we developed a mouse model restricting LacZ to thymic stromal cotransporter (TSCOT)-expressing thymic stromal cells...

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Bibliographic Details
Main Authors: Sejin Ahn, Gwanghee Lee, Soo Jung Yang, Deokjae Lee, Seunghyuk Lee, Hyo Sun Shin, Min Cheol Kim, Kee Nyung Lee, Douglas C Palmer, Marc R Theoret, Eric J Jenkinson, Graham Anderson, Nicholas P Restifo, Moon Gyo Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2494558?pdf=render