Transcriptomic Evaluation of Pulmonary Fibrosis-Related Genes: Utilization of Transgenic Mice with Modifying p38 Signal in the Lungs

Transcriptomic Evaluation of Pulmonary Fibrosis-Related Genes: Utilization of Transgenic Mice with Modifying p38 Signal in the Lungs

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing lung disease that is caused by the dysregulation of alveolar epithelial type II cells (AEC II). The mechanisms involved in the progression of IPF remain incompletely understood, although the immune response accompanied by p38 mitogen-act...

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Bibliographic Details
Main Authors: Shuichi Matsuda, Jun-Dal Kim, Fumihiro Sugiyama, Yuji Matsuo, Junji Ishida, Kazuya Murata, Kanako Nakamura, Kana Namiki, Tatsuhiko Sudo, Tomoyuki Kuwaki, Masahiko Hatano, Koichiro Tatsumi, Akiyoshi Fukamizu, Yoshitoshi Kasuya
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
p38 mitogen-activated protein kinase
bleomycin-induced pulmonary fibrosis
idiopathic pulmonary fibrosis
RNA sequencing
alveolar epithelial type II cells
Online Access:https://www.mdpi.com/1422-0067/21/18/6746

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https://www.mdpi.com/1422-0067/21/18/6746

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