Calcium-containing scaffolds induce bone regeneration by regulating mesenchymal stem cell differentiation and migration

Calcium-containing scaffolds induce bone regeneration by regulating mesenchymal stem cell differentiation and migration

Abstract Background Osteoinduction and subsequent bone formation rely on efficient mesenchymal stem cell (MSC) recruitment. It is also known that migration is induced by gradients of growth factors and cytokines. Degradation of Ca2+-containing biomaterials mimics the bone remodeling compartment prod...

Full description

Bibliographic Details
Main Authors: Rubén Aquino-Martínez, Alcira P. Angelo, Francesc Ventura Pujol
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Stem Cell Research & Therapy
Subjects:
Osteoinduction
Mesenchymal stem cells
Migration
Bone grafts
Calcium sulfate
Bone morphogenetic protein
Online Access:http://link.springer.com/article/10.1186/s13287-017-0713-0

Internet

http://link.springer.com/article/10.1186/s13287-017-0713-0

Similar Items