Novel Apoptotic Mediators Identified by Conservation of Vertebrate Caspase Targets

Caspases are proteases conserved throughout Metazoans and responsible for initiating and executing the apoptotic program. Currently, there are over 1800 known apoptotic caspase substrates, many of them known regulators of cell proliferation and death, which makes them attractive therapeutic targets....

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Bibliographic Details
Main Authors: Nina Gubina, Dominique Leboeuf, Konstantin Piatkov, Maxim Pyatkov
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/4/612