FIH permits NAA10 to catalyze the oxygen-dependent lysyl-acetylation of HIF-1α
The N-terminal acetyltransferase A (NatA) complex, which is composed of NAA10 and NAA15, catalyzes N-terminal acetylation of many proteins in a co-translational manner. Structurally, the catalytic subunit NAA10 was believed to have no activity toward an internal lysine residue because the gate of it...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-10-01
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Series: | Redox Biology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231718305421 |