A DFT-Based QSARs Study of Acetazolamide/Sulfanilamide Derivatives with Carbonic Anhydrase (CA-II) Isozyme Inhibitory Activity

A DFT-Based QSARs Study of Acetazolamide/Sulfanilamide Derivatives with Carbonic Anhydrase (CA-II) Isozyme Inhibitory Activity

This study presents Quantitative Structure Activity Relationships (QSAR) studyon a pool of 18 bio-active sulfonamide compounds which includes five acetazolamidederivatives, eight sulfanilamide derivatives and five clinically used sulfonamides moleculesas drugs namely acetazolamide, methazolamide, di...

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Bibliographic Details
Main Authors: Oral Oltulu, Selami Palaz, Semra Güler, Hasan Türkmen, Erol Eroğlu
Format: Article
Language:English
Published: MDPI AG 2007-02-01
Series:International Journal of Molecular Sciences
Subjects:
Sulfonamides
carbonic anhydrase (CA-II) inhibitors
QSAR
DFT
Online Access:http://www.mdpi.com/1422-0067/8/2/145/

Internet

http://www.mdpi.com/1422-0067/8/2/145/

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