Mechanisms of xenogeneic baboon platelet aggregation and phagocytosis by porcine liver sinusoidal endothelial cells.

Mechanisms of xenogeneic baboon platelet aggregation and phagocytosis by porcine liver sinusoidal endothelial cells.

Baboons receiving xenogeneic livers from wild type and transgenic pigs survive less than 10 days. One of the major issues is the early development of profound thrombocytopenia that results in fatal hemorrhage. Histological examination of xenotransplanted livers has shown baboon platelet activation,...

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Bibliographic Details
Main Authors: Qiang Peng, Heidi Yeh, Lingling Wei, Keiichi Enjyoj, Zurab Machaidze, Eva Csizmad, Christian Schuetz, Kang Mi Lee, Shaoping Deng, Simon C Robson, James Markmann, Leo Buhler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3484054?pdf=render

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http://europepmc.org/articles/PMC3484054?pdf=render

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