Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-κB activation

Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-κB activation

<p>Abstract</p> <p>Background</p> <p>Osteopontin (OPN), a secreted phosphoglycoprotein, has been strongly associated with tumor progression and aggressive cancers. MDA-MB-435 cells secrete very high levels of OPN. However metastasis-suppressed MDA-MB-435 cells, which we...

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Bibliographic Details
Main Authors: Chambers Ann F, Chandramouli Kondethimmana H, Metge Brandon J, Cicek Muzaffer, Fillmore Rebecca A, Clark David W, Samant Rajeev S, Casey Graham, Welch Danny R, Shevde Lalita A
Format: Article
Language:English
Published: BMC 2007-01-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/6/1/6

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http://www.molecular-cancer.com/content/6/1/6

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