Impact of ApoE Polymorphism and Physical Activity on Plasma Antioxidant Capability and Erythrocyte Membranes

Impact of ApoE Polymorphism and Physical Activity on Plasma Antioxidant Capability and Erythrocyte Membranes

The allele epsilon 4 (ε4) of apolipoprotein E (ApoE) is the strongest genetic risk factor for Alzheimer’s disease (AD). ApoE protein plays a pivotal role in the synthesis and metabolism of amyloid beta (Aβ), the major component of the extracellular plaques that constitute AD pathological hallmarks....

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Bibliographic Details
Main Authors: Rebecca Piccarducci, Simona Daniele, Jonathan Fusi, Lucia Chico, Filippo Baldacci, Gabriele Siciliano, Ubaldo Bonuccelli, Ferdinando Franzoni, Claudia Martini
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Antioxidants
Subjects:
apoe ε4
physical activity
erythrocytes
oxidative stress
cellular membrane
amyloid beta
Online Access:https://www.mdpi.com/2076-3921/8/11/538

Internet

https://www.mdpi.com/2076-3921/8/11/538

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