Impact of ApoE Polymorphism and Physical Activity on Plasma Antioxidant Capability and Erythrocyte Membranes
The allele epsilon 4 (ε4) of apolipoprotein E (ApoE) is the strongest genetic risk factor for Alzheimer’s disease (AD). ApoE protein plays a pivotal role in the synthesis and metabolism of amyloid beta (Aβ), the major component of the extracellular plaques that constitute AD pathological hallmarks....
Main Authors: | Rebecca Piccarducci, Simona Daniele, Jonathan Fusi, Lucia Chico, Filippo Baldacci, Gabriele Siciliano, Ubaldo Bonuccelli, Ferdinando Franzoni, Claudia Martini |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-11-01
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Series: | Antioxidants |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3921/8/11/538 |
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