Oxidative Stress and β-Thalassemic Erythroid Cells behind the Molecular Defect

β-thalassemia is a worldwide distributed monogenic red cell disorder, characterized by the absence or reduced β-globin chain synthesis. Despite the extensive knowledge of the molecular defects causing β-thalassemia, less is known about the mechanisms responsible for the associated ineffective eryth...

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Bibliographic Details
Main Authors: Lucia De Franceschi, Mariarita Bertoldi, Alessandro Matte, Sara Santos Franco, Antonella Pantaleo, Emanuela Ferru, Franco Turrini
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2013/985210