Measurement of Bradykinin Formation and Degradation in Blood Plasma: Relevance for Acquired Angioedema Associated With Angiotensin Converting Enzyme Inhibition and for Hereditary Angioedema Due to Factor XII or Plasminogen Gene Variants

Measurement of Bradykinin Formation and Degradation in Blood Plasma: Relevance for Acquired Angioedema Associated With Angiotensin Converting Enzyme Inhibition and for Hereditary Angioedema Due to Factor XII or Plasminogen Gene Variants

Bradykinin (BK)-mediated angioedema (AE) states are rare acquired or hereditary conditions involving localized edema of the subcutaneous and submucosal tissues. Citrated plasma from healthy volunteers or patients with hereditary angioedema (HAE) with normal level of C1-inhibitor (C1-INH) was used to...

Full description

Bibliographic Details
Main Authors: François Marceau, Georges E. Rivard, Julie M. Gauthier, Karen E. Binkley, Arnaud Bonnefoy, Isabelle Boccon-Gibod, Laurence Bouillet, Matthieu Picard, Ghislain Levesque, Hannah Laure Elfassy, Hélène Bachelard, Jacques Hébert, Konrad Bork
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Medicine
Subjects:
B2 receptors
bradykinin
hereditary angioedema with normal C1 inhibitor level
kallikreins
tissue plasminogen activator
plasmin
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00358/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2020.00358/full

Similar Items