miR-214 ameliorates acute kidney injury via targeting DKK3 and activating of Wnt/β-catenin signaling pathway
Abstract Background miR-214 was demonstrated to be upregulated in models of renal disease and promoted fibrosis in renal injury independent of TGF-β signaling in vivo. However, the detailed role of miR-214 in acute kidney injury (AKI) and its underlying mechanism are still largely unknown. Methods I...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-09-01
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Series: | Biological Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s40659-018-0179-2 |