Pharmacokinetics of Macrolide Antibiotics and Transport into the Interstitial Fluid: Comparison among Erythromycin, Clarithromycin, and Azithromycin
Recent research has found higher levels and longer total exposure of azithromycin, a macrolide antibiotic agent, in the interstitial fluid of the skin than in the plasma. This unique distribution is expected to contribute to its antimicrobial activity at the primary infection site. However, it remai...
Main Authors: | Shinji Kobuchi, Teruhiko Kabata, Koki Maeda, Yukako Ito, Toshiyuki Sakaeda |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
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Series: | Antibiotics |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-6382/9/4/199 |
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