Type 2 Diabetes Alters Vascular Cannabinoid Receptor 1 Expression, Phosphorylation Status, and Vasorelaxation in Rat Aorta

Type 2 Diabetes Alters Vascular Cannabinoid Receptor 1 Expression, Phosphorylation Status, and Vasorelaxation in Rat Aorta

Previous studies have suggested a role of the endocannabinoid system in metabolic diseases, such as diabetes. We investigated the effect of diabetes on cannabinoid receptor type 1 (CB<sub>1</sub>) expression and cannabinoid-induced vasorelaxation in rat aorta rings. Aortas from healthy r...

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Bibliographic Details
Main Authors: Enrique Sánchez-Pastor, Xóchitl Trujillo, Christian Ramos-Flores, Mónica Ríos-Silva, Felipa Andrade, Yolitzy Cárdenas, Elena Castro, Zorayda Urzúa, Oscar Newton-Sánchez, Miguel Huerta
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
cannabinoid
diabetes
CB<sub>1</sub> receptor expression
vasorelaxation
CNR1
Online Access:https://www.mdpi.com/1420-3049/25/21/4948

Internet

https://www.mdpi.com/1420-3049/25/21/4948

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