MicroRNA-106b Regulates Expression of the Tumour Suppressors p21 and TXNIP and Promotes Tumour Cell Proliferation in Mycosis Fungoides

MicroRNA-106b Regulates Expression of the Tumour Suppressors p21 and TXNIP and Promotes Tumour Cell Proliferation in Mycosis Fungoides

A prognostic 3-miRNA classifier for early-stage mycosis fungoides has been developed recently, with miR-106b providing the strongest prognostic power. The aim of this study was to investigate the molecular function of miR-106b in mycosis fungoides disease progression. The cellular localization of mi...

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Bibliographic Details
Main Authors: Lise M. Lindahl, Maria Gluud, Thomas Emmanuel, Emil A. Thomsen, Tengpeng Hu, Anne H. Rittig, Pamela Celis, Veronica Stolearenco, Thorbjørn Krejsgaard, Claus Johansen, Andreas Willerslev-Olsen, Terkild B. Buus, Anders Woetmann, Lars Aagaard, Carsten Geisler, Thomas Litman, Jacob G. Mikkelsen, Niels Odum, Lars Iversen
Format: Article
Language:English
Published: Society for Publication of Acta Dermato-Venereologica 2020-09-01
Series:Acta Dermato-Venereologica
Subjects:
mycosis fungoides
cutaneous t-cell lymphoma
microrna
progression
tumour suppressors
p21
txnip
Online Access: https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3574

Internet

https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3574

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