Induction of Oxidative Stress Responses by Dioxin and other Ligands of the Aryl Hydrocarbon Receptor

TCDD and other polyhalogenated aromatic hydrocarbon ligands of the aryl hydrocarbon receptor (AHR) have been classically considered as non-genotoxic compounds because they fail to be directly mutagenic in either bacteria or most in vitro assay systems. They do so in spite of having repeatedly been l...

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Bibliographic Details
Main Authors: John F. Reichard, Timothy P. Dalton, Howard G. Shertzer, Alvaro Puga
Format: Article
Language:English
Published: SAGE Publishing 2005-07-01
Series:Dose-Response
Online Access:https://doi.org/10.2203/dose-response.003.03.003