Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue by rapamycin

Tuberous Sclerosis Complex (TSC) is a multiorgan genetic disease that prominently features brain malformations (tubers) with many patients suffering from epilepsy and autism. These malformations typically exhibit neuronal as well as glial cell abnormalities and likely underlie much of the neurologic...

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Bibliographic Details
Main Authors: Robert P. Carson, Dominic L. Van Nielen, Peggy A. Winzenburger, Kevin C. Ess
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111002907