Virulence Role of the GlcNAc Side Chain of the Lancefield Cell Wall Carbohydrate Antigen in Non-M1-Serotype Group A Streptococcus

Classification of streptococci is based upon expression of unique cell wall carbohydrate antigens. All serotypes of group A Streptococcus (GAS; Streptococcus pyogenes), a leading cause of infection-related mortality worldwide, express the group A carbohydrate (GAC). GAC, the classical Lancefield ant...

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Bibliographic Details
Main Authors: Anna Henningham, Mark R. Davies, Satoshi Uchiyama, Nina M. van Sorge, Sean Lund, Kelsey T. Chen, Mark J. Walker, Jason N. Cole, Victor Nizet, Indranil Biswas
Format: Article
Language:English
Published: American Society for Microbiology 2018-01-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/9/1/e02294-17