Pressure Combined with Ischemia/Reperfusion Injury Induces Deep Tissue Injury via Endoplasmic Reticulum Stress in a Rat Pressure Ulcer Model

Pressure Combined with Ischemia/Reperfusion Injury Induces Deep Tissue Injury via Endoplasmic Reticulum Stress in a Rat Pressure Ulcer Model

Pressure ulcer is a complex and significant health problem in long-term bedridden patients, and there is currently no effective treatment or efficient prevention method. Furthermore, the molecular mechanisms and pathogenesis contributing to the deep injury of pressure ulcers are unclear. The aim of...

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Bibliographic Details
Main Authors: Fei-Fei Cui, Ying-Ying Pan, Hao-Huang Xie, Xiao-Hui Wang, Hong-Xue Shi, Jian Xiao, Hong-Yu Zhang, Hao-Teng Chang, Li-Ping Jiang
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:International Journal of Molecular Sciences
Subjects:
pressure ulcer
deep tissue injury
endoplasmic reticulum stress
Akt/GSK3β pathway
rat model
Online Access:http://www.mdpi.com/1422-0067/17/3/284

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http://www.mdpi.com/1422-0067/17/3/284

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