Single-Cell Droplet Microfluidic Screening for Antibodies Specifically Binding to Target Cells

Summary: Monoclonal antibodies are a main player in modern drug discovery. Many antibody screening formats exist, each with specific advantages and limitations. Nonetheless, it remains challenging to screen antibodies for the binding of cell-surface receptors (the most important class of all drug ta...

Full description

Bibliographic Details
Main Authors: Nachiket Shembekar, Hongxing Hu, David Eustace, Christoph A. Merten
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718301359