Pharmacokinetic predictions and docking studies of substituted aryl amine-based triazolopyrimidine designed inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH)

Pharmacokinetic predictions and docking studies of substituted aryl amine-based triazolopyrimidine designed inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH)

Abstract Background The sixteen (16) designed data set of substituted aryl amine-based triazolopyrimidine were docked against Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) employing Molegro Virtual Docker (MVD) software and their pharmacokinetic property determined through SwissADME p...

Full description

Bibliographic Details
Main Authors: Zakari Ya’u Ibrahim, Adamu Uzairu, Gideon Adamu Shallangwa, Stephen Eyije Abechi
Format: Article
Language:English
Published: SpringerOpen 2021-07-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Docking simulation
Pharmacokinetic
SwissADME prediction
Substituted aryl amine-based triazolopyrimidine
PfDHODH
Online Access:https://doi.org/10.1186/s43094-021-00288-2

Internet

https://doi.org/10.1186/s43094-021-00288-2

Similar Items