Features of resistance-associated substitutions after failure of multiple direct-acting antiviral regimens for hepatitis C

Features of resistance-associated substitutions after failure of multiple direct-acting antiviral regimens for hepatitis C

Background & Aims: We aimed to clarify the features of resistance-associated substitutions (RASs) after failure of multiple interferon (IFN)-free regimens in HCV genotype 1b infections. Methods: A total of 1,193 patients with HCV for whom direct-acting antiviral (DAA) treatment had failed we...

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Bibliographic Details
Main Authors: Jun Itakura, Masayuki Kurosaki, Satoru Kakizaki, Keisuke Amano, Nobuaki Nakayama, Jun Inoue, Tetsu Endo, Hiroyuki Marusawa, Chitomi Hasebe, Kouji Joko, Shuichi Wada, Takehiro Akahane, Youhei Koushima, Chikara Ogawa, Tatsuya Kanto, Masashi Mizokami, Namiki Izumi
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:JHEP Reports
Subjects:
Resistance-associated substitution
Hepatitis C virus
Direct acting antiviral
P32del
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555920300720

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http://www.sciencedirect.com/science/article/pii/S2589555920300720

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