Mucosal Administration of Cycle-Di-Nucleotide-Adjuvanted Virosomes Efficiently Induces Protection against Influenza H5N1 in Mice

The need for more effective influenza vaccines is highlighted by the emergence of novel influenza strains, which can lead to new pandemics. There is a growing population of susceptible subjects at risk for severe complications of influenza, such as the elderly who are only in part protected by curre...

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Bibliographic Details
Main Authors: Thomas Ebensen, Jennifer Debarry, Gabriel K. Pedersen, Paulina Blazejewska, Sebastian Weissmann, Kai Schulze, Kenneth C. McCullough, Rebecca J. Cox, Carlos A. Guzmán
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01223/full