Peripheral nervous system genes expressed in central neurons induce growth on inhibitory substrates.

Peripheral nervous system genes expressed in central neurons induce growth on inhibitory substrates.

Trauma to the spinal cord and brain can result in irreparable loss of function. This failure of recovery is in part due to inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans (CSPGs). Peripheral nervous system (PNS) neurons exhibit increased regenerative ability compared...

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Bibliographic Details
Main Authors: William J Buchser, Robin P Smith, Jose R Pardinas, Candace L Haddox, Thomas Hutson, Lawrence Moon, Stanley R Hoffman, John L Bixby, Vance P Lemmon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3368946?pdf=render

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http://europepmc.org/articles/PMC3368946?pdf=render

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