Three Types of Functional Regulatory T Cells Control T Cell Responses at the Human Maternal-Fetal Interface

Three Types of Functional Regulatory T Cells Control T Cell Responses at the Human Maternal-Fetal Interface

Summary: During pregnancy, maternal regulatory T cells (Tregs) are important in establishing immune tolerance to invading fetal extravillous trophoblasts (EVTs). CD25HIFOXP3+ Tregs are found at high levels in decidual tissues and have been shown to suppress fetus-specific and nonspecific responses....

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Bibliographic Details
Main Authors: Maria Salvany-Celades, Anita van der Zwan, Marilen Benner, Vita Setrajcic-Dragos, Hannah Ananda Bougleux Gomes, Vidya Iyer, Errol R. Norwitz, Jack L. Strominger, Tamara Tilburgs
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719305996

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http://www.sciencedirect.com/science/article/pii/S2211124719305996

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