Mechanical Ventilation Impairs IL-17 Cytokine Family Expression in Ventilator-Associated Pneumonia

Mechanical Ventilation Impairs IL-17 Cytokine Family Expression in Ventilator-Associated Pneumonia

Mechanical ventilation (MV) is the primary risk factor for the development of ventilator-associated pneumonia (VAP). Besides inducing a pro-inflammatory T-helper (Th)-1 cytokine response, MV also induces an anti-inflammatory Th2 cytokine response, marked by increased IL-4 secretion and reduced bacte...

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Bibliographic Details
Main Authors: Fien H. R. De Winter, Bart ’s Jongers, Kenny Bielen, Domenico Mancuso, Leen Timbermont, Christine Lammens, Vincent Van averbeke, Jan Boddaert, Omar Ali, Jan Kluytmans, Alexey Ruzin, Surbhi Malhotra-Kumar, Philippe G. Jorens, Herman Goossens, Samir Kumar-Singh
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
mechanical ventilation
ventilator-associated pneumonia
vap
<i>pseudomonas aeruginosa</i>
il-17
il-17a
il-22
ifnγ
Online Access:https://www.mdpi.com/1422-0067/20/20/5072

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https://www.mdpi.com/1422-0067/20/20/5072

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