Sleep and Wake Affect Glycogen Content and Turnover at Perisynaptic Astrocytic Processes

Astrocytic glycogen represents the only form of glucose storage in the brain, and one of the outcomes of its breakdown is the production of lactate that can be used by neurons as an alternative energetic substrate. Since brain metabolism is higher in wake than in sleep, it was hypothesized that glyc...

Full description

Bibliographic Details
Main Authors: Michele Bellesi, Luisa de Vivo, Samuel Koebe, Giulio Tononi, Chiara Cirelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00308/full