Frizzled-9+ Supporting Cells Are Progenitors for the Generation of Hair Cells in the Postnatal Mouse Cochlea

Frizzled-9+ Supporting Cells Are Progenitors for the Generation of Hair Cells in the Postnatal Mouse Cochlea

Lgr5+ cochlear supporting cells (SCs) have been reported to be hair cell (HC) progenitor cells that have the ability to regenerate HCs in the neonatal mouse cochlea, and these cells are regulated by Wnt signaling. Frizzled-9 (Fzd9), one of the Wnt receptors, has been reported to be used to mark neur...

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Bibliographic Details
Main Authors: Shasha Zhang, Dingding Liu, Ying Dong, Zhong Zhang, Yuan Zhang, Han Zhou, Lingna Guo, Jieyu Qi, Ruiying Qiang, Mingliang Tang, Xia Gao, Chunjie Zhao, Xiaoyun Chen, Xiaoyun Qian, Renjie Chai
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Frizzled-9 (Fzd9)
cochlea
hair cell progenitor
hair cell generation
self-renew
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00184/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2019.00184/full

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