Pyrimidoindole derivative UM171 enhances derivation of hematopoietic progenitor cells from human pluripotent stem cells

In the field of hematopoietic regeneration, deriving hematopoietic stem cells (HSCs) from pluripotent stem cells with engraftment potential is the central mission. Unstable hematopoietic differentiation protocol due to variation factors such as serums and feeder cells, remains a major technical issu...

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Bibliographic Details
Main Authors: Xuejia Li, Chengxiang Xia, Tongjie Wang, Lijuan Liu, Qianhao Zhao, Dan Yang, Fangxiao Hu, Mengyun Zhang, Ke Huang, Yang Geng, Yi Zheng, Yuxian Guan, Hongling Wu, Xiaoli Chen, Guangjin Pan, Jiekai Chen, Juan Du, Jinyong Wang
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506117300521