Memory B cells targeting SARS-CoV-2 spike protein and their dependence on CD4+ T cell help

Memory B cells targeting SARS-CoV-2 spike protein and their dependence on CD4+ T cell help

Summary: Memory B cells seem to be more durable than antibodies and thus crucial for the long-term immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Here we investigate SARS-CoV-2 spike-specific memory B cells and their dependence on CD4+ T cell help in differe...

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Bibliographic Details
Main Authors: Jernej Pušnik, Enrico Richter, Bianca Schulte, Ramona Dolscheid-Pommerich, Christian Bode, Christian Putensen, Gunther Hartmann, Galit Alter, Hendrik Streeck
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Cell Reports
Subjects:
SARS-CoV-2
COVID-19
memory B cells
spike
CD4+ T cell
IL-21
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721006963

Internet

http://www.sciencedirect.com/science/article/pii/S2211124721006963

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