Evaluation of encapsulated liver cell spheroids in a fluidised-bed bioartificial liver for treatment of ischaemic acute liver failure in pigs in a translational setting.

Evaluation of encapsulated liver cell spheroids in a fluidised-bed bioartificial liver for treatment of ischaemic acute liver failure in pigs in a translational setting.

Liver failure is an increasing problem. Donor-organ shortage results in patients dying before receiving a transplant. Since the liver can regenerate, alternative therapies providing temporary liver-support are sought. A bioartificial-liver would temporarily substitute function in liver failure buyin...

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Bibliographic Details
Main Authors: Clare Selden, Catherine Wendy Spearman, Delawir Kahn, Malcolm Miller, Anthony Figaji, Eloy Erro, James Bundy, Isobel Massie, Sherri-Ann Chalmers, Hiram Arendse, Aude Gautier, Peter Sharratt, Barry Fuller, Humphrey Hodgson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3867376?pdf=render

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http://europepmc.org/articles/PMC3867376?pdf=render

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