Role of histone deacetylases in gene regulation at nuclear lamina.

Role of histone deacetylases in gene regulation at nuclear lamina.

Theoretical models suggest that gene silencing at the nuclear periphery may involve "closing" of chromatin by transcriptional repressors, such as histone deacetylases (HDACs). Here we provide experimental evidence confirming these predictions. Histone acetylation, chromatin compactness, an...

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Bibliographic Details
Main Authors: Beatrice C Milon, Haibo Cheng, Mikhail V Tselebrovsky, Sergei A Lavrov, Valentina V Nenasheva, Elena A Mikhaleva, Yuri Y Shevelyov, Dmitry I Nurminsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3511463?pdf=render

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http://europepmc.org/articles/PMC3511463?pdf=render

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