Descending motor circuitry required for NT-3 mediated locomotor recovery after spinal cord injury in mice

Descending motor circuitry required for NT-3 mediated locomotor recovery after spinal cord injury in mice

Neurotrophin-3 (NT-3) plays a key role in the growth, development, and function of the nervous system. Here the authors show that NT-3-induced propriospino-motoneuron circuit reorganization is critical for locomotor recovery in mice following spinal cord injury.

Bibliographic Details
Main Authors: Qi Han, Josue D. Ordaz, Nai-Kui Liu, Zoe Richardson, Wei Wu, Yongzhi Xia, Wenrui Qu, Ying Wang, Heqiao Dai, Yi Ping Zhang, Christopher B. Shields, George M. Smith, Xiao-Ming Xu
Format: Article
Language:English
Published: Nature Publishing Group 2019-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13854-3

Internet

https://doi.org/10.1038/s41467-019-13854-3

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