Rck of Salmonella Typhimurium Delays the Host Cell Cycle to Facilitate Bacterial Invasion

Rck of Salmonella Typhimurium Delays the Host Cell Cycle to Facilitate Bacterial Invasion

Salmonella Typhimurium expresses on its outer membrane the protein Rck which interacts with the epidermal growth factor receptor (EGFR) of the plasma membrane of the targeted host cells. This interaction activates signaling pathways, leading to the internalization of Salmonella. Since EGFR plays a k...

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Bibliographic Details
Main Authors: Julien Mambu, Emilie Barilleau, Laetitia Fragnet-Trapp, Yves Le Vern, Michel Olivier, Guillaume Sadrin, Olivier Grépinet, Frédéric Taieb, Philippe Velge, Agnès Wiedemann
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Salmonella Typhimurium
cell cycle
DNA damage
checkpoint response
cyclomodulin
invasion
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2020.586934/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2020.586934/full

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