Of mice, flies – and men? Comparing fungal infection models for large-scale screening efforts

Of mice, flies – and men? Comparing fungal infection models for large-scale screening efforts

Studying infectious diseases requires suitable hosts for experimental in vivo infections. Recent years have seen the advent of many alternatives to murine infection models. However, the use of non-mammalian models is still controversial because it is often unclear how well findings from these system...

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Bibliographic Details
Main Authors: Sascha Brunke, Jessica Quintin, Lydia Kasper, Ilse D. Jacobsen, Martin E. Richter, Ekkehard Hiller, Tobias Schwarzmüller, Christophe d'Enfert, Karl Kuchler, Steffen Rupp, Bernhard Hube, Dominique Ferrandon
Format: Article
Language:English
Published: The Company of Biologists 2015-05-01
Series:Disease Models & Mechanisms
Subjects:
Candida glabrata
Mutant library
Drosophila melanogaster
Alternative infection models
Signature-tagged mutagenesis
Fungal virulence factors
Online Access:http://dmm.biologists.org/content/8/5/473

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http://dmm.biologists.org/content/8/5/473

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