Methodological considerations for identifying multiple plasma proteins associated with all-cause mortality in a population-based prospective cohort

Abstract Novel methods to characterize the plasma proteome has made it possible to examine a wide range of proteins in large longitudinal cohort studies, but the complexity of the human proteome makes it difficult to identify robust protein-disease associations. Nevertheless, identification of indiv...

Full description

Bibliographic Details
Main Authors: Isabel Drake, George Hindy, Peter Almgren, Gunnar Engström, Jan Nilsson, Olle Melander, Marju Orho-Melander
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85991-z