Theoretical characterisation of strand cross-correlation in ChIP-seq
Abstract Background Strand cross-correlation profiles are used for both peak calling pre-analysis and quality control (QC) in chromatin immunoprecipitation followed by sequencing (ChIP-seq) analysis. Despite its potential for robust and accurate assessments of signal-to-noise ratio (S/N) because of...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-09-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-020-03729-6 |