An Ethanolic Extract of Ampelopsis Radix Exerts Anti-colorectal Cancer Effects and Potently Inhibits STAT3 Signaling In Vitro

An Ethanolic Extract of Ampelopsis Radix Exerts Anti-colorectal Cancer Effects and Potently Inhibits STAT3 Signaling In Vitro

Colorectal cancer (CRC) is a leading cause of cancer-related morbidity and mortality worldwide. Signal transducer and activator of transcription 3 (STAT3) signaling is constantly activated in CRC, and has been proposed as a pathogenic factor and a therapeutic target of CRC. Ampelopsis Radix (AR), a...

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Bibliographic Details
Main Authors: Zhi-Ling Yu, Tao Su, Jing-Xuan Bai, Ying-Jie Chen, Xin-Ning Wang, Xiu-Qiong Fu, Ting Li, Hui Guo, Pei-Li Zhu, Yue Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Pharmacology
Subjects:
Ampelopsis Radix
colorectal cancer
STAT3
apoptosis
migration
invasion
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00227/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00227/full

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