The Role of Oncogenic Tyrosine Kinase NPM-ALK in Genomic Instability

Genomic stability is crucial for cell life and transmitting genetic material is one of the primary tasks of the cell. The cell needs to be able to recognize any possible error and quickly repair it, and thus, cells have developed several mechanisms to detect DNA damage and promote repair during evol...

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Bibliographic Details
Main Authors: Cosimo Lobello, Vasilis Bikos, Andrea Janikova, Sarka Pospisilova
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Cancers
Subjects:
ALK
p53
Online Access:http://www.mdpi.com/2072-6694/10/3/64