Impact of a Single Point Mutation on the Antimicrobial and Fibrillogenic Properties of Cryptides from Human Apolipoprotein B

Impact of a Single Point Mutation on the Antimicrobial and Fibrillogenic Properties of Cryptides from Human Apolipoprotein B

Host defense peptides (HDPs) are gaining increasing interest, since they are endowed with multiple activities, are often effective on multidrug resistant bacteria and do not generally lead to the development of resistance phenotypes. Cryptic HDPs have been recently identified in human apolipoprotein...

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Bibliographic Details
Main Authors: Rosa Gaglione, Giovanni Smaldone, Angela Cesaro, Mariano Rumolo, Maria De Luca, Rocco Di Girolamo, Luigi Petraccone, Pompea Del Vecchio, Rosario Oliva, Eugenio Notomista, Emilia Pedone, Angela Arciello
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pharmaceuticals
Subjects:
bioactive cryptides
single point mutation
anti-biofilm activity
in vitro fibrillogenesis
Online Access:https://www.mdpi.com/1424-8247/14/7/631

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https://www.mdpi.com/1424-8247/14/7/631

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