AKR1B10 promotes breast cancer cell proliferation and migration via the PI3K/AKT/NF-κB signaling pathway

AKR1B10 promotes breast cancer cell proliferation and migration via the PI3K/AKT/NF-κB signaling pathway

Abstract Background Aberrant expression of Aldo-Keto reductase family 1 member B10 (AKR1B10) was associated with tumor size and metastasis of breast cancer in our published preliminary studies. However, little is known about the detailed function and underlying molecular mechanism of AKR1B10 in the...

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Bibliographic Details
Main Authors: Jiayao Qu, Jia Li, Yaming Zhang, Rongzhang He, Xiangting Liu, Ke Gong, Lili Duan, Weihao Luo, Zheng Hu, Gengsheng Wang, Chenglai Xia, Dixian Luo
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Cell & Bioscience
Subjects:
AKR1B10
PI3K/AKT
NF-κB
Proliferation
Migration
Breast cancer
Online Access:https://doi.org/10.1186/s13578-021-00677-3

Internet

https://doi.org/10.1186/s13578-021-00677-3

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