Overexpression of sterol carrier protein-2 differentially alters hepatic cholesterol accumulation in cholesterol-fed mice

Although in vitro studies suggest a role for sterol carrier protein-2 (SCP-2) in cholesterol trafficking and metabolism, the physiological significance of these observations remains unclear. This issue was addressed by examining the response of mice overexpressing physiologically relevant levels of...

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Bibliographic Details
Main Authors: Barbara P. Atshaves, Avery L. McIntosh, Gregory G. Martin, Danilo Landrock, H. Ross Payne, Shivaprasad Bhuvanendran, Kerstin K. Landrock, Olga I. Lyuksyutova, Jeffery D. Johnson, Ronald D. Macfarlane, Ann B. Kier, Friedhelm Schroeder
Format: Article
Language:English
Published: Elsevier 2009-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520307902