Recombinant expression of Streptococcus pneumoniae capsular polysaccharides in Escherichia coli

Currently, Streptococcus pneumoniae is responsible for over 14 million cases of pneumonia worldwide annually, and over 1 million deaths, the majority of them children. The major determinant for pathogenesis is a polysaccharide capsule that is variable and is used to distinguish strains based on thei...

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Bibliographic Details
Main Authors: Emily J. Kay, Laura E. Yates, Vanessa S. Terra, Jon Cuccui, Brendan W. Wren
Format: Article
Language:English
Published: The Royal Society 2016-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.150243