Increased matrix metalloproteinase (MMPs) levels do not predict disease severity or progression in emphysema.

Increased matrix metalloproteinase (MMPs) levels do not predict disease severity or progression in emphysema.

Though matrix metalloproteinases (MMPs) are critical in the pathogenesis of COPD, their utility as a disease biomarker remains uncertain. This study aimed to determine whether bronchoalveolar lavage (BALF) or plasma MMP measurements correlated with disease severity or functional decline in emphysema...

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Bibliographic Details
Main Authors: Jeanine M D'Armiento, Monica P Goldklang, Andrew A Hardigan, Patrick Geraghty, Michael D Roth, John E Connett, Robert A Wise, Frank C Sciurba, Steven M Scharf, Jincy Thankachen, Monirul Islam, Andrew J Ghio, Robert F Foronjy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3575373?pdf=render

Internet

http://europepmc.org/articles/PMC3575373?pdf=render

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