NEDD4-1 regulates migration and invasion of glioma cells through CNrasGEF ubiquitination in vitro.

Neuronal precursor cell-expressed developmentally down-regulated 4-1 (NEDD4-1) plays a great role in tumor cell growth, but its function and mechanism in cell invasive behavior are totally unknown. Here we report that NEDD4-1 regulates migration and invasion of malignant glioma cells via triggering...

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Bibliographic Details
Main Authors: Hao Zhang, Wenchen Nie, Xu Zhang, Gentang Zhang, Zhiqiang Li, Huaibing Wu, Qiong Shi, Yong Chen, Zhijun Ding, Xiuping Zhou, Rutong Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3858320?pdf=render