Differential effects of light and feeding on circadian organization of peripheral clocks in a forebrain Bmal1 mutant

In order to assess the contribution of a central clock in the hypothalamic suprachiasmatic nucleus (SCN) to circadian behavior and the organization of peripheral clocks, we generated forebrain/SCN-specific Bmal1 knockout mice by using floxed Bmal1 and pan-neuronal Cre lines. The forebrain knockout m...

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Bibliographic Details
Main Authors: Mariko Izumo, Martina Pejchal, Andrew C Schook, Ryan P Lange, Jacqueline A Walisser, Takashi R Sato, Xiaozhong Wang, Christopher A Bradfield, Joseph S Takahashi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/04617